• DOI:10.1038/35097076
Corpus ID: 4421562

A forkhead-domain gene is mutated in a severe speech and language disorder

@article{Lai2001AFG,
  title={A forkhead-domain gene is mutated in a severe speech and language disorder},
  author={C. Lai and S. Fisher and J. Hurst and F. Vargha-Khadem and A. Monaco},
  journal={Nature},
  year={2001},
  volume={413},
  pages={519-523}
}

C. Lai, S. Fisher, +2 authors A. Monaco

Published 2001

Biology, Medicine

Nature

Individuals affected with developmental disorders of speech and language have substantial difficulty acquiring expressive and/or receptive language in the absence of any profound sensory or neurological impairment and despite adequate intelligence and opportunity. [...] Key Result Here we show that the gene FOXP2, which encodes a putative transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain, is directly disrupted by the translocation breakpoint in CS.Expand Abstract

View on Nature

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed