A fluorescence polarization-based assay for peptidyl prolyl cis/trans isomerase cyclophilin A.

Abstract

Peptidyl prolyl cis/trans isomerase cyclophilin A (CypA) serves as a cellular receptor for the important immunosuppressant drug, cyclosporin A. In addition, CypA and its enzyme family have been found to play critical roles in a variety of biological processes, including protein trafficking, HIV and HCV infection/replication, and Ca(2+)-mediated… (More)

Topics

Cite this paper

@article{Liu2006AFP, title={A fluorescence polarization-based assay for peptidyl prolyl cis/trans isomerase cyclophilin A.}, author={Yaya Liu and Jianjun Jiang and Paul L. Richardson and Rajarathnam D Reddy and Donald D Johnson and Warren M Kati}, journal={Analytical biochemistry}, year={2006}, volume={356 1}, pages={100-7} }