A fluorescence digital image microscopy system for quantifying relative cell numbers in tissue culture plates.

@article{Proffitt1996AFD,
  title={A fluorescence digital image microscopy system for quantifying relative cell numbers in tissue culture plates.},
  author={Robert T. Proffitt and J. V. Tran and C Patrick Reynolds},
  journal={Cytometry},
  year={1996},
  volume={24 3},
  pages={204-13}
}
Microwell tissue culture plates provide a convenient format for conducting cell growth and cellular cytotoxicity assays, but such assays often have a limited dynamic range. We have developed the digital imaging microscopy scanning system (DIM-SCAN), which is a semiautomated fluorescence digital imaging system for quantifying relative cell numbers in situ in a variety of tissue culture plate formats, especially 96-well plates. The system consists of an epifluorescence inverted microscope with a… CONTINUE READING

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