A flexible perforated microelectrode array for extended neural recordings

@article{Boppart1992AFP,
  title={A flexible perforated microelectrode array for extended neural recordings},
  author={Stephen Ao Boppart and Bruce C. Wheeler and C. B. Wallace},
  journal={IEEE Transactions on Biomedical Engineering},
  year={1992},
  volume={39},
  pages={37-42}
}
A flexible and perforated 32-element planar microelectrode array has been fabricated and used to measure evoked potentials in brain slices. Electrodes are spaced 200 mu m apart in a 4*8 array and are sandwiched between layers of insulating polyimide. The polyimide sandwich is lifted off its substrate, making it flexible so that it could be shaped to contoured tissues. Prior to liftoff, holes are etched to expose recording sites 15 mu m in diameter and to create perforations which allow… 

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References

SHOWING 1-10 OF 15 REFERENCES

Recording from the Aplysia Abdominal Ganglion with a Planar Microelectrode Array

A passive multimicroelectrode array has been fabricated and used to record neural events from the abdominal ganglion of the marine mollusk, Aplysia californica, and can record large numbers of unique and often interrelated extracellular neural potentials in relatively simple experiments.

A Practical 24 Channel Microelectrode for Neural Recording in Vivo

A multichannel microelectrode that has 24 recording sites, spaced at 85 ¿m intervals along the edge of its tip, that can be arranged as a 1 ×24 linear array along one edge or as a 2 ×12 array along both edges.

Simultaneous Single Unit Recording in vitro with a Photoetched Laser Deinsulated Gold Multimicroelectrode Surface

  • G. Gross
  • Biology
    IEEE Transactions on Biomedical Engineering
  • 1979
Flat photoetched gold conductors, situated on a glass plate and deinsulated at their tips with single 8 ns UV laser pulses, have been utilized to record single unit extra-cellular activity from brain ganglia of the snail Helix pomatia.

A Peripheral Nerve Information Transducer for Amputees: Long-Term Multichannel Recordings from Rabbit Peripheral Nerves

  • D. Edell
  • Engineering
    IEEE Transactions on Biomedical Engineering
  • 1986
Pertinent materials, fabrication, and surgical implantation issues are discussed, and possible use of the sensor as a source for a binary code suitable for communication of information to a computer is presented along with discussion of the limitations of the current technology and possible future applications.

Scaling limitations of silicon multichannel recording probes

The scaling limitations of multichannel recording probes fabricated for use in neurophysiology using silicon integrated circuit technologies are described and the effects of scaling probe dimensions on its strength and stiffness are described.