A fish oil diet does not reverse insulin resistance despite decreased adipose tissue TNF-alpha protein concentration in ApoE-3*Leiden mice.

@article{Muurling2003AFO,
  title={A fish oil diet does not reverse insulin resistance despite decreased adipose tissue TNF-alpha protein concentration in ApoE-3*Leiden mice.},
  author={Martin Muurling and Ronald P Mensink and Hanno Pijl and Johannes Anthonius Romijn and Louis M. Havekes and Peter Jacobus Voshol},
  journal={The Journal of nutrition},
  year={2003},
  volume={133 11},
  pages={3350-5}
}
Dietary interventions with fish oil have been found to protect against the development of high-fat diet-induced insulin resistance and to decrease the expression of tumor necrosis factor (TNF)-alpha. However, the effect of fish oil administration on preexisting insulin resistance is subject to debate. In the present study, we examined the mechanism by which fish oil affects preexisting insulin resistance. High fat diet-induced insulin-resistant ApoE*3-Leiden transgenic mice were treated for 10… CONTINUE READING