A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A.

@article{Spencer2002AFT,
  title={A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A.},
  author={Kevin Sim{\~o}es Spencer and Kypros H. Nicolaides},
  journal={Prenatal diagnosis},
  year={2002},
  volume={22 10},
  pages={877-9}
}
This study examines 45 cases of trisomy 13 and 59 cases of trisomy 18 and reports an algorithm to identify pregnancies with a fetus affected by trisomy 13 or 18 by a combination of maternal age fetal nuchal translucency (NT) thickness, and maternal serum free beta-hCG and PAPP-A at 11-14 weeks of gestation. In this mixed trisomy group the median MoM NT was increased at 2.819, whilst the median MoMs for free beta-hCG and PAPP-A were reduced at 0.375 and 0.201 respectively. We predict that with… CONTINUE READING
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Series FM1 no

  • Office of National Statistics.
  • 28. Birth statistics (1999). Stationery Office…
  • 2000

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