A firing-rate model of spike-frequency adaptation in sinusoidally-driven thalamocortical relay neurons

@inproceedings{Smith2001AFM,
  title={A firing-rate model of spike-frequency adaptation in sinusoidally-driven thalamocortical relay neurons},
  author={Gregory Douglas Smith and Charles L. Cox and S Murray Sherman and John Rinzel},
  year={2001}
}
In a systematic study of thalamocortical relay neuron responses to sinusoidal current injection [J. Neurophysiol. 83 (1), 588], we found that the Fourier fundamental of tonic responses was regularly phase advanced during low temporal frequency stimulation (1/10 cycles at 0.1 Hz). We hypothesized that such phase advances of the Fourier fundamental response were due to a slow spike-frequency adaptation. Here we measure the time-dependence of the instantaneous firing rate during a current pulse… CONTINUE READING

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