A fibrinogen-binding protein of Staphylococcus epidermidis.

  title={A fibrinogen-binding protein of Staphylococcus epidermidis.},
  author={Martin Nilsson and Lars Frykberg and J. I. Flock and Lei Pei and Martin Lindberg and Bengt Guss},
  journal={Infection and immunity},
  volume={66 6},
The present study reports on fibrinogen (Fg) binding of Staphylococcus epidermidis. Adhesion of different S. epidermidis strains to immobilized Fg was found to vary significantly between different strains, and the component responsible was found to be proteinaceous in nature. To further characterize the Fg-binding activity, a shotgun phage display library covering the S. epidermidis chromosome was constructed. By affinity selection (panning) against immobilized Fg, a phagemid clone, pSEFG1, was… CONTINUE READING
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