A fast transient potassium current in thalamic relay neurons: kinetics of activation and inactivation.

@article{Huguenard1991AFT,
  title={A fast transient potassium current in thalamic relay neurons: kinetics of activation and inactivation.},
  author={John R. Huguenard and Douglas A. Coulter and David A. Prince},
  journal={Journal of neurophysiology},
  year={1991},
  volume={66 4},
  pages={1304-15}
}
1. Whole-cell voltage-clamp techniques were used to record K+ currents in relay neurons (RNs) that had been acutely isolated from rat thalamic ventrobasal complex and maintained at 23 degrees C in vitro. Tetrodoxin (TTX; 0.5 microM) was used to block Na+ currents, and reduced extracellular levels of Ca2+ (1 mM) were used to minimize contributions from Ca2+ current (ICa). 2. In RNs, depolarizing commands activate K+ currents characterized by a substantial rapidly inactivating (time constant… CONTINUE READING
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