A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana.

@article{Zhang2004AFO,
  title={A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana.},
  author={P. Zhang and B. Chomel and M. Schau and J. S. Goo and S. Droz and K. Kelminson and S. George and N. Lerche and J. Koehler},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 37},
  pages={
          13630-5
        }
}
  • P. Zhang, B. Chomel, +6 authors J. Koehler
  • Published 2004
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
Bartonella species are fastidious, Gram-negative human pathogens that can persist in the host bloodstream for years and bind to and invade several types of host cells. For many pathogens, adhesion to host cells and extracellular matrix (ECM) components is a critical virulence determinant. Bacteria often vary expression of surface adhesins by phase or antigenic variation to subvert the host immune response and permit adaptive interaction with different host structures. We developed a macaque… Expand
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