A family of transmembrane microneme proteins of Toxoplasma gondii contain EGF-like domains and function as escorters.

@article{Meissner2002AFO,
  title={A family of transmembrane microneme proteins of Toxoplasma gondii contain EGF-like domains and function as escorters.},
  author={Markus Meissner and Matthias Reiss and Nicola K. Viebig and Vern B Carruthers and Catherine Toursel and Stanislas Tomavo and James W. Ajioka and Dominique Soldati},
  journal={Journal of cell science},
  year={2002},
  volume={115 Pt 3},
  pages={563-74}
}
TgMIC6, TgMIC7, TgMIC8 and TgMIC9 are members of a novel family of transmembrane proteins localized in the micronemes of the protozoan parasite Toxoplasma gondii. These proteins contain multiple epidermal growth factor-like domains, a putative transmembrane spanning domain and a short cytoplasmic tail. Sorting signals to the micronemes are encoded in this short tail. We established previously that TgMIC6 serves as an escorter for two soluble adhesins, TgMIC1 and TgMIC4. Here, we present the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 51 extracted citations

Identification and characterization of a microneme protein (NcMIC6) in Neospora caninum

Parasitology Research • 2015
View 10 Excerpts
Highly Influenced

Research advances in microneme protein 3 of Toxoplasma gondii

Parasites & Vectors • 2015
View 6 Excerpts
Highly Influenced

Synergistic role of micronemal proteins in Toxoplasma gondii virulence

The Journal of experimental medicine • 2005
View 9 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 40 references

The microneme protein

N. Garcia-Reguet, M. Lebrun, +7 authors J. F. Dubremetz
2000
View 6 Excerpts
Highly Influenced

EtMIC4: A microneme protein

F. M. Tomley, K. J. Billington, J. M. Bumstead, J. M. Clarke, Monaghan
2002

Identification and characterisation of an Escorter for two secretory adhesins

Mol. Microbiol
2001

Similar Papers

Loading similar papers…