A family of textilinin genes, two of which encode proteins with antihaemorrhagic properties

@article{Filippovich2002AFO,
  title={A family of textilinin genes, two of which encode proteins with antihaemorrhagic properties},
  author={I. Filippovich and N. Sorokina and P. Masci and J. de Jersey and A. Whitaker and D. Winzor and P. Gaffney and M. Lavin},
  journal={British Journal of Haematology},
  year={2002},
  volume={119}
}
Summary. Two peptides, textilinins 1 and 2, isolated from the venom of the Australian common brown snake, Pseudonaja textilis textilis, are effective in preventing blood loss. To further investigate the potential of textilinins as antihaemorrhagic agents, we cloned cDNAs encoding these proteins. The isolated full‐length cDNA (430 bp in size) was shown to code for a 59 amino acid protein, corresponding in size to the native peptide, plus an additional 24 amino acid propeptide. Six such cDNAs… Expand
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