A family of fatty acid binding receptors.

  title={A family of fatty acid binding receptors.},
  author={Andrew J Brown and Steven Jupe and Celia P Briscoe},
  journal={DNA and cell biology},
  volume={24 1},
The family of G protein-coupled receptors (GPCRs) serves as the target for almost a third of currently marketed drugs, and provides the predominant mechanism through which extracellular factors transmit signals to the cell. The discovery of GPCRs with no known ligand has initiated a frenzy of research, with the aim of elucidating the physiological ligands for these "orphan" receptors and revealing new drug targets. The GPR40 family of receptors, tandemly located on chromosome 19q13.1, exhibit… CONTINUE READING

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