A family of clostridial and streptococcal ligand-binding proteins with conserved C-terminal repeat sequences.

@article{Wren1991AFO,
  title={A family of clostridial and streptococcal ligand-binding proteins with conserved C-terminal repeat sequences.},
  author={Brendan W. Wren},
  journal={Molecular microbiology},
  year={1991},
  volume={5 4},
  pages={797-803}
}
Analysis of the derived amino acid sequences of toxins A and B from Clostridium difficile has identified an extraordinarily large number of repeat amino acid units in the C-terminal regions of the proteins. Nearly one third of each of the proteins consist of repeating units which appear, at least in the case of toxin A, to be responsible for carbohydrate binding. Similar repeat units are also found in the C-terminal region of four glucosyltransferases from Streptococcus mutans and Streptococcus… CONTINUE READING