A family-based and case-control association study of the NOTCH4 gene and schizophrenia

@article{Fan2002AFA,
  title={A family-based and case-control association study of the NOTCH4 gene and schizophrenia},
  author={Jia Bing Fan and Jie Xin Tang and N F Gu and Guo Yin Feng and Fei Zou and Ya Li Xing and Jian Guo Shi and Shu-jiang Zhao and Shao Ming Zhu and Linong Ji and Wei-sheng Sun and Youliang Zheng and Wen-qi Liu and Gerome Breen and David M. St Clair and Lin He},
  journal={Molecular Psychiatry},
  year={2002},
  volume={7},
  pages={100-103}
}
Recently a strong positive association between schizophrenia and Notch4 has been reported.1 Both individual markers and haplotypes showed association with the disease, with five markers (three microsatellites and two SNPs) being tested. In order to test this finding we genotyped these markers in the Han Chinese population using a sample of 544 cases and 621 controls as well as >300 trios. Analysis of allele, genotype and haplotype frequencies in both samples showed no association between the… CONTINUE READING
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