A fail-safe system for the ribosome under zinc-limiting conditions in Bacillus subtilis.

@article{Natori2007AFS,
  title={A fail-safe system for the ribosome under zinc-limiting conditions in Bacillus subtilis.},
  author={Yousuke Natori and Hideaki Nanamiya and Genki Akanuma and Saori Kosono and Toshiaki Kudo and Kozo Ochi and Fujio Kawamura},
  journal={Molecular microbiology},
  year={2007},
  volume={63 1},
  pages={294-307}
}
As zinc is an essential trace metal ion for all living cells, cells elaborate a variety of strategies to cope with zinc starvation. In Bacillus subtilis, genes encoding ribosomal proteins L31 and S14 are duplicated into two types: one type contains a zinc-binding motif (RpmE or RpsN), whereas the other does not (YtiA or YhzA). We have previously shown that displacement of RpmE (L31) by YtiA from already assembled ribosomes is controlled by zinc, and this replacement could contribute to zinc… CONTINUE READING

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