A factor known to bind to endogenous Ig heavy chain enhancer only in lymphocytes is a ubiquitously active transcription factor.

Abstract

The transcriptional enhancer located in the first intron of the immunoglobulin heavy chain constant region is a major determinant of B-cell-specific expression of immunoglobulin genes. Like other enhancers, the Ig heavy chain enhancer contains several short sequence motifs that bind specific transcription factors. Each binding site contributes to the… (More)

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Cite this paper

@article{Elmaleh1990AFK, title={A factor known to bind to endogenous Ig heavy chain enhancer only in lymphocytes is a ubiquitously active transcription factor.}, author={N Elmaleh and Patrick Matthias and William Schaffner}, journal={European journal of biochemistry}, year={1990}, volume={187 3}, pages={507-13} }