A dyshomeostasis of electrolytes and trace elements in acute stressor states: impact on the heart.

@article{Whitted2010ADO,
  title={A dyshomeostasis of electrolytes and trace elements in acute stressor states: impact on the heart.},
  author={Anthony D Whitted and John W Stanifer and Preeti Dube and Brian J Borkowski and Jawwad Yusuf and Babatunde O Komolafe and Richard C. Davis and Judith E Soberman and Karl T. Weber},
  journal={The American journal of the medical sciences},
  year={2010},
  volume={340 1},
  pages={48-53}
}
Acute stressor states are associated with a homeostatic activation of the hypothalamic-pituitary-adrenal axis. A hyperadrenergic state follows and leads to a dyshomeostasis of several intra- and extracellular cations, including K, Mg, and Ca. Prolongation of myocardial repolarization and corrected QT interval (QTc) of the ECG are useful biomarkers of hypokalemia and/or hypomagnesemia and should be monitored to address the adequacy of cation replacement. A dyshomeostasis of several trace… CONTINUE READING