A dynamic model of the meningococcal transferrin receptor.

  title={A dynamic model of the meningococcal transferrin receptor.},
  author={I C Boulton and Andrew R. Gorringe and J K Shergill and Christopher L. Joannou and Robert Evans},
  journal={Journal of theoretical biology},
  volume={198 4},
Iron is an essential nutrient for all organisms and consequently, the ability to bind transferrin and sequester iron from his source constitutes a distinct advantage to a blood-borne bacterial pathogen. Levels of free iron are strictly limited in human serum, largely through the action of the iron-binding protein transferrin. The acquisition of trasferrin-iron is coincident with pathogenicity among Neisseria species and a limited number of other pathogens of human and veterinary significance… CONTINUE READING

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