A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes.

  title={A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes.},
  author={Terje Sagvolden and Espen Borg{\aa} Johansen and Heidi Aase and Vivienne Ann Russell},
  journal={The Behavioral and brain sciences},
  volume={28 3},
          397-419; discussion 419-68
Attention-deficit/hyperactivity disorder (ADHD) is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Inattentiveness, overactivity, and impulsiveness are presently regarded as the main clinical symptoms. The dynamic developmental behavioral theory is based on the hypothesis that altered dopaminergic function plays a pivotal role by failing to modulate nondopaminergic (primarily glutamate and GABA) signal transmission appropriately. A… 

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The reward-related mechanisms underlying the interactions between executive function, behavior regulation and impulsivity in PBD and ADHD may be differentially compromised, and in accordance differently shape the clinical symptoms of impulsivity and goal-directed behavior.

An integrative theory of attention-deficit/ hyperactivity disorder based on the cognitive and affective neurosciences

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  • Biology, Psychology
    Journal of Neuroscience Methods
  • 2007

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The combined insights of the articles presented here suggest that there is no brain damage in ADHD, but hypo-efficient dopamine systems which give rise to neurochemical imbalances which cause behavioural problems: deficits in sustained attention, overactivity and impulsiveness.

Functional deficits in basal ganglia of children with attention-deficit/hyperactivity disorder shown with functional magnetic resonance imaging relaxometry

A new functional magnetic resonance imaging procedure (T2 relaxometry) was developed to indirectly assess blood volume in the striatum (caudate and putamen) of boys 6–12 years of age in steady-state conditions and found boys with attention-deficit/hyperactivity disorder had higher T2 relaxation time measures in the putamen bilaterally than healthy control subjects.

Developmental neuropsychopathology of attention deficit and impulsiveness

  • E. Taylor
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    Development and Psychopathology
  • 1999
This formulation emphasizes the need for several types of research: the mapping of biological findings onto different components of disorder, the combination of genetically informative designs with direct measurement of relevant aspects of the environment, and the use of longitudinal studies to examine predictive and mediating factors separately for different aspects of outcome.

Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD.

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  • Psychology, Biology
    Psychological bulletin
  • 1997
A theoretical model that links inhibition to 4 executive neuropsychological functions that appear to depend on it for their effective execution is constructed and finds it to be strongest for deficits in behavioral inhibition, working memory, regulation of motivation, and motor control in those with ADHD.