A dual-pathway ultrastructural model for the tight junction of rat proximal tubule epithelium.

@article{Guo2003ADU,
  title={A dual-pathway ultrastructural model for the tight junction of rat proximal tubule epithelium.},
  author={P. Guo and A. M. Weinstein and S. Weinbaum},
  journal={American journal of physiology. Renal physiology},
  year={2003},
  volume={285 2},
  pages={
          F241-57
        }
}
A dual-pathway model is proposed for transport across the tight junction (TJ) in rat proximal tubule: large slit breaks formed by infrequent discontinuities in the TJ complex and numerous small circular pores, with spacing similar to that of claudin-2. This dual-pathway model is developed in the context of a proximal tubule model (Weinstein AM. Am J Physiol Renal Fluid Electrolyte Physiol 247: F848-F862, 1984) to provide an ultrastructural view of solute and water fluxes. Tubule model paramters… Expand
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References

SHOWING 1-10 OF 41 REFERENCES
Application of a fiber-matrix model to transport in renal tubules
Water permeability and pathways in the proximal tubule.
  • C. A. Berry
  • Chemistry, Medicine
  • The American journal of physiology
  • 1983
Claudin-2 is selectively expressed in proximal nephron in mouse kidney.
Transport by epithelia with compliant lateral intercellular spaces: asymmetric oncotic effects across the rat proximal tubule.
Evidence for transcellular osmotic water flow in rat proximal tubules.
Physical properties of isolated perfused renal tubules and tubular basement membranes.
Claudins create charge-selective channels in the paracellular pathway between epithelial cells.
Coupled water transport by rat proximal tubule.
Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers.
Microvascular permeability.
...
1
2
3
4
5
...