A dual fate of the hindlimb muscle mass: cloacal/perineal musculature develops from leg muscle cells.

@article{Valek2005ADF,
  title={A dual fate of the hindlimb muscle mass: cloacal/perineal musculature develops from leg muscle cells.},
  author={Petr Val{\'a}{\vs}ek and Darrell J. R. Evans and Flavio Maina and Milo{\vs} Grim and Ketan B. Patel},
  journal={Development},
  year={2005},
  volume={132 3},
  pages={447-58}
}
The cloaca serves as a common opening to the urinary and digestive systems. In most mammals, the cloaca is present only during embryogenesis, after which it undergoes a series of septation events leading to the formation of the anal canal and parts of the urogenital tract. During embryogenesis it is surrounded by skeletal muscle. The origin and the mechanisms regulating the development of these muscles have never been determined. Here, we show that the cloacal muscles of the chick originate… CONTINUE READING

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