A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach.

@article{Possemiers2013ADY,
  title={A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach.},
  author={Sam Possemiers and I. M. R. Pinheiro and A F M Verhelst and Pieter van den Abbeele and Lois Maignien and Debby Laukens and Stuart G. Reeves and Larry E. Robinson and Thomas Raas and Yves-Jacques Schneider and Tom Richard Van de Wiele and Massimo Marzorati},
  journal={Journal of agricultural and food chemistry},
  year={2013},
  volume={61 39},
  pages={9380-92}
}
EpiCor, derived from Saccharomyces cerevisiae, has been shown to have immunomodulating properties in human clinical trials and in vitro. However, the underlying mechanisms behind its immune protection via the gut remain largely unknown. Therefore, the aim of this study was to use an integrated in vitro approach to evaluate the metabolism of EpiCor by the intestinal microflora, its modulating effect on the gut microbiota, and its anti-inflammatory activity on human-derived cell lines. Using the… CONTINUE READING
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