A double-switch system regulates male courtship behavior in male and female Drosophila melanogaster

@article{Shirangi2006ADS,
  title={A double-switch system regulates male courtship behavior in male and female Drosophila melanogaster},
  author={Troy R. Shirangi and Barbara J. Taylor and Michael Aidan McKeown},
  journal={Nature Genetics},
  year={2006},
  volume={38},
  pages={1435-1439}
}
Current models describe male-specific fruitless (fruM) as a genetic 'switch' regulating sexual behavior in Drosophila melanogaster, and they postulate that female (F) and male (M) doublesex (dsx) products control body sexual morphology. In contradiction to this simple model, we show that dsx, as well as fruM and non–sex-specific retained (retn), affect both male and female sexual behaviors. In females, both retn and dsxF contribute to female receptivity, and both genes act to repress male-like… CONTINUE READING
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