A double-blind trial of treatment of seborrhoeic dermatitis with 2% ketoconazole cream compared with 1% hydrocortisone cream.

@article{Katsambas1989ADT,
  title={A double-blind trial of treatment of seborrhoeic dermatitis with 2% ketoconazole cream compared with 1% hydrocortisone cream.},
  author={Andreas D Katsambas and Ch G Antoniou and Efi Frangouli and Georgia Avgerinou and Dimitrios Michailidis and J T Stratigos},
  journal={The British journal of dermatology},
  year={1989},
  volume={121 3},
  pages={353-7}
}
Fifty patients with seborrhoeic dermatitis were treated with 2% ketoconazole cream (n = 24) or with 1% hydrocortisone cream (n = 26) for 4 weeks in a double-blind comparative study. These twice daily applications resulted in 87.2% symptomatic improvement for hydrocortisone vs. 81.6% for ketoconazole. The number of P. ovale yeasts was significantly reduced after the application of ketoconazole compared with hydrocortisone. The incidence of side-effects was low in both groups. 

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