A double-blind study of L-threonine in patients with spinal spasticity.

@article{Lee1993ADS,
  title={A double-blind study of L-threonine in patients with spinal spasticity.},
  author={Adrian Lee and Victor Patterson},
  journal={Acta neurologica Scandinavica},
  year={1993},
  volume={88 5},
  pages={334-8}
}
We conducted a double-blind, placebo-controlled, crossover study of oral L-threonine at 6 g/day in patients with spinal spasticity. Muscle tone from selected leg muscles, measured by the Ashworth Scale, was the principal measure of spasticity and was evaluated before and at the end of each treatment period. A 10% reduction in Ashworth score was regarded as a positive response to a treatment. The results were analyzed sequentially, patients being classified as threonine-responders, placebo… CONTINUE READING

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