A double-blind randomized trial: prophylactic vasopressin reduces hypotension after cardiopulmonary bypass.

@article{Morales2003ADR,
  title={A double-blind randomized trial: prophylactic vasopressin reduces hypotension after cardiopulmonary bypass.},
  author={David Lu{\'i}s Sim{\'o}n Morales and Mauricio J Garrido and John D Madigan and David N Helman and Joseph Faber and Mathew Russell Williams and Donald W. Landry and Mehmet C. Oz},
  journal={The Annals of thoracic surgery},
  year={2003},
  volume={75 3},
  pages={926-30}
}
BACKGROUND Inhibition of angiotensin-converting enzyme (ACE) predisposes patients to vasodilatory hypotension after cardiopulmonary bypass (CPB). This hypotension has been correlated with arginine vasopressin deficiency and can be corrected by its replacement. In patients receiving ACE inhibition, we investigated whether initiation of vasopressin before CPB would diminish post-CPB hypotension and catecholamine use by avoiding vasopressin deficiency. METHODS Cardiac surgical patients on ACE… CONTINUE READING

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