A double-blind placebo-controlled trial of a leukotriene receptor antagonist in chronic pancreatitis in humans.

@article{Cartmell2004ADP,
  title={A double-blind placebo-controlled trial of a leukotriene receptor antagonist in chronic pancreatitis in humans.},
  author={Mark Timothy Cartmell and D O'reilly and C. S. Porter and A. Kingsnorth},
  journal={Journal of hepato-biliary-pancreatic surgery},
  year={2004},
  volume={11 4},
  pages={255-9}
}
BACKGROUND/PURPOSE Chronic pancreatitis is a debilitating condition of which pain is a predominant feature, and, at present, only putative treatments, beyond analgesics, exist. Evidence suggests that leukotrienes may play a role in both acute and chronic pancreatitis and that cells involved in their signalling are implicated in both conditions and pain production in chronic pancreatitis. We thus performed a study of a cysteinyl leukotriene receptor antagonist of proven benefit in chronic asthma… CONTINUE READING