A double-blind group comparison of mianserin and clomipramine in the treatment of mildly depressed psychiatric out-patients.

@article{Dunbar1985ADG,
  title={A double-blind group comparison of mianserin and clomipramine in the treatment of mildly depressed psychiatric out-patients.},
  author={G. C. Dunbar and Mikko Naarala and H. A. Hiltunen},
  journal={Acta psychiatrica Scandinavica. Supplementum},
  year={1985},
  volume={320},
  pages={60-6}
}
The effects of mianserin 30-60 mg and clomipramine 75-150 mg were compared in a randomized double-blind study of 62 mildly depressed out-patients. Treatment was continued for three to four weeks, after which approximately 50% of patients left the study clinically much improved. Significant benefits for mianserin were apparent at days 7 and 21 on the Hamilton Depression Rating Scale (HDRS) total score and at day 7 on the HDRS anxiety-somatization factor score. No difference in overall… CONTINUE READING

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