A double-blind dose-reduction trial of fluphenazine decanoate for chronic, unstable schizophrenic patients.


OBJECTIVE This study evaluated the feasibility and impact of gradually reducing relatively high doses of fluphenazine decanoate by one-half for chronically impaired, poor inner-city patients with schizophrenia. METHOD Forty-three patients currently receiving an average of 23 mg (0.3 mg/kg) of fluphenazine decanoate every 2 weeks were divided alternately… (More)