A double blind cross over trial of theophylline prophylaxis for sleep hypoxaemia in Duchenne muscular dystrophy.

@article{Khan1997ADB,
  title={A double blind cross over trial of theophylline prophylaxis for sleep hypoxaemia in Duchenne muscular dystrophy.},
  author={Yaseen Khan and John Heckmatt},
  journal={Neuromuscular disorders : NMD},
  year={1997},
  volume={7 2},
  pages={75-80}
}
Twelve non-ambulant patients with Duchenne muscular dystrophy underwent a double-blind cross-over clinical trial of slow-release theophylline for the treatment of asymptomatic sleep hypoxaemia. Eight channel polysomnography was carried out at home to identify patients with sleep hypoxaemia and this was repeated whilst on the theophylline and placebo limbs… CONTINUE READING