A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression.

@article{Mazidi2016ADR,
  title={A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression.},
  author={Mohsen Mazidi and Maryam Shemshian and Seyed Mohammad Hadi Mousavi and Abdolreza Norouzy and Tayebe Kermani and Toktam Moghiman and Akram Sadeghi and Naghme Mokhber and Majid Ghayour-Mobarhan and Gordon A A Ferns},
  journal={Journal of complementary & integrative medicine},
  year={2016},
  volume={13 2},
  pages={195-9}
}
BACKGROUND Depression and anxiety are prevalent serious psychiatric disorders. Several drugs are used to treat these conditions but these are often associated with serious side effects. For this reason alternative therapies, including herbal medication such as saffron, have been proposed. We aimed to assess the effects of saffron extract for the treatment of anxiety and depression using a 12-week double-blind, placebo-controlled trial design. METHODS Sixty adult patients with anxiety and… CONTINUE READING