A double-blind, randomized, placebo-controlled trial of paroxetine controlled-release in irritable bowel syndrome.

@article{Masand2009ADR,
  title={A double-blind, randomized, placebo-controlled trial of paroxetine controlled-release in irritable bowel syndrome.},
  author={Prakash S. Masand and Chi-Un Pae and Stan Krulewicz and Kathleen S Peindl and Paolo Mannelli and Indu M. Varia and Ashwin A. Patkar},
  journal={Psychosomatics},
  year={2009},
  volume={50 1},
  pages={78-86}
}
BACKGROUND Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disease that causes significant impairment in quality of life and accounts for $8 billion per year to the healthcare system and loss of productivity in the workplace. OBJECTIVE The authors examined the efficacy and safety of paroxetine controlled-release (paroxetine-CR) in patients with IBS. METHOD Seventy-two patients with IBS participated in a 12-week, double-blind, randomized, placebo-controlled study of… CONTINUE READING

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