A double-blind, randomized, placebo-controlled trial of prostaglandin E1 in liver transplantation.

@article{Henley1995ADR,
  title={A double-blind, randomized, placebo-controlled trial of prostaglandin E1 in liver transplantation.},
  author={Keith S. Henley and Michael R Lucey and Daniel P Normolle and Robert M. Merion and I. Douglas McLaren and B A Crider and D S Mackie and Victoria L Shieck and Timothy T. Nostrant and Kimberly Ann Brown},
  journal={Hepatology},
  year={1995},
  volume={21 2},
  pages={366-72}
}
A double-blind placebo-controlled trial of intravenous prostaglandin PGE1 (40 micrograms/h) was conducted in adult orthotopic liver transplant recipients. Infusion was started intraoperatively and continued for up to 21 days. Patients were followed up for 180 days postoperatively. Among 172 patients eligible for treatment in the study, 160 could be evaluated (78 PGE1; 82 placebo). Patient and graft survival were similar (PGE1: 16 deaths, 9 retransplantations [7 survivors]; controls: 15 deaths… CONTINUE READING
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