A double-blind, placebo-controlled crossover trial of nadolol and verapamil in mild and moderately symptomatic hypertrophic cardiomyopathy.

@article{Gilligan1993ADP,
  title={A double-blind, placebo-controlled crossover trial of nadolol and verapamil in mild and moderately symptomatic hypertrophic cardiomyopathy.},
  author={David M. Gilligan and Wan Leong Chan and J K Joshi and Peter Clarke and Astrid Elizabeth Fletcher and Steve J Krikler and Celia M. Oakley},
  journal={Journal of the American College of Cardiology},
  year={1993},
  volume={21 7},
  pages={1672-9}
}
OBJECTIVES The aim of this study was to determine whether therapy with a beta-adrenergic or calcium channel blocking agent can improve the functional capacity and quality of life of patients with mild or moderately symptomatic hypertrophic cardiomyopathy. BACKGROUND Both beta-blockers and calcium channel blockers may alleviate symptoms in hypertrophic cardiomyopathy, but previous studies have been performed in hospitalized patients or have been open studies without control subjects. METHODS… CONTINUE READING

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