A double-blind, placebo-controlled, dose-response study of the effectiveness and safety of lisinopril for children with hypertension.

@article{Soffer2003ADP,
  title={A double-blind, placebo-controlled, dose-response study of the effectiveness and safety of lisinopril for children with hypertension.},
  author={Beth A Soffer and Zhongxin Zhang and Kenneth Miller and Beth A. Vogt and Shahnaz Shahinfar},
  journal={American journal of hypertension},
  year={2003},
  volume={16 10},
  pages={795-800}
}
BACKGROUND Despite widespread use in hypertensive children, the safety and effectiveness of lisinopril had not been previously tested in a controlled study. METHODS This study explored the dose-response relationship and safety of lisinopril in 115 hypertensive children, aged 6 to 16 years. Patients were randomized in a double-blind fashion for 2 weeks to one of three doses by body weight at baseline: <50 kg: low (0.625 mg), middle (2.5 mg), high (20 mg), and > or =50 kg: low (1.25 mg), middle… CONTINUE READING
41 Citations
11 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 11 references

A double - blind , placebo - controlled , dose response study of the effectiveness and safety of enalapril for children with hypertension

  • GJ Schwartz, GB Haycock, CM Edelman, AA Spitzer
  • J Clin Pharmacol
  • 2002

Update on the 1987 Task Force Report on high blood pressure in children and adolescents : National High Blood Pressure Education Program

  • KC Thompson, Z Zhao, JM Mazakas, CA Beasley, RA Reed, CL Moser
  • Pediatrics
  • 1996

Epidemiology and measurement of high blood pressure in children and adolescents

  • RJ Prineas, EM Elkwiry
  • 1992

Epidemiology and measurement of high blood pressure in children and adolescents, in Loggie JMH (ed): Pediatric and Adolescent Hypertension

  • RJ Prineas, EM Elkwiry
  • Oxford, Blackwell Scien- tific Publications,
  • 1992

Report of the task force on blood pressure control in children

  • AR Sinaiko
  • Pediatrics
  • 1977

Similar Papers

Loading similar papers…