A double-blind, dose-response study of midodrine in neurogenic orthostatic hypotension.

@article{Wright1998ADD,
  title={A double-blind, dose-response study of midodrine in neurogenic orthostatic hypotension.},
  author={Richard A Wright and Horacio Kaufmann and Rachithri Perera and Tonette L. Opfer-Gehrking and M. A. McElligott and Kunwei Sheng and Phillip A. Low},
  journal={Neurology},
  year={1998},
  volume={51 1},
  pages={120-4}
}
OBJECTIVE To determine the best therapeutic strategy for the use of midodrine in patients with neurogenic orthostatic hypotension (NOH). BACKGROUND Midodrine is a peripherally acting alpha-adrenergic agonist useful in the treatment of NOH. However, neither the most effective dosage of midodrine nor the required frequency of administration is established. DESIGN/METHODS Midodrine dose-blood pressure response, pharmacokinetics, and duration of action were examined in a double-blind, placebo… CONTINUE READING

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