A dose-response study of the effects of biosynthetic human growth hormone on formation and strength of granulation tissue.

@article{Jrgensen1987ADS,
  title={A dose-response study of the effects of biosynthetic human growth hormone on formation and strength of granulation tissue.},
  author={Peter Holmberg J\orgensen and Troels Torp Andreassen},
  journal={Endocrinology},
  year={1987},
  volume={121 5},
  pages={1637-41}
}
The dose-response relationship between biosynthetic human GH (b-hGH) and biomechanical properties (maximum stress, strain at maximum stress, relative failure energy, and maximum stiffness) and collagen deposition of granulation tissue in sc implanted cellulose sponges were investigated after 7 days of implantation in female rats. GH was administered in doses of 0.5, 2.0, and 8.0 mg/kg body weight/day. In the first part of the experiment, treatment with b-hGH started 7 days before implantation… CONTINUE READING
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