A dose-ranging study of ranitidine and its effect on intragastric and intra-oesophageal acidity in subjects with gastro-oesophageal reflux disease.

@article{Thomson1994ADS,
  title={A dose-ranging study of ranitidine and its effect on intragastric and intra-oesophageal acidity in subjects with gastro-oesophageal reflux disease.},
  author={Alan B. R. Thomson and L Babiuk and P. Kirdeikis and Lori Zuk and Barbara J Marriage and K B Bowes},
  journal={Alimentary pharmacology & therapeutics},
  year={1994},
  volume={8 4},
  pages={443-51}
}
METHODS This randomized, double-blind, single-centre, crossover study was designed to assess the effects of three regimens of ranitidine (150 mg b.d., 300 mg b.d. and 300 mg q.d.s.) and placebo on intra-oesophageal and intragastric pH in subjects with gastro-oesophageal reflux disease (GERD). Twenty-six subjects were screened, and 9 were evaluable by the… CONTINUE READING