A dose ranging study of ibuprofen suspension as an antipyretic.

@article{Marriott1991ADR,
  title={A dose ranging study of ibuprofen suspension as an antipyretic.},
  author={Sheila Marriott and Tammy J Stephenson and Dale Hull and Robert Pownall and Christopher M. Smith and A Butler},
  journal={Archives of disease in childhood},
  year={1991},
  volume={66 9},
  pages={1037-41; discussion 1041-2}
}
A double blind trial was conducted to determine the dose of ibuprofen suspension, which is effective in reducing the body temperature. The principal measure of efficacy was a reduction in axillary temperature of 1 degree C or more three hours after dosing. A second objective of the trial was to compare the incidence and severity of side effects and the palatability of a range of ibuprofen doses. Ninety three children were included in the analysis. All four doses of ibuprofen studied (0.625 mg… CONTINUE READING

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