A dose escalation trial of fixed dose gemcitabine and capecitabine.

Abstract

12026 Background: Gemcitabine can be administered as a 30-minute infusion or a prolonged, fixed-dose infusion (FDR). FDR may have improved clinical activity. Gemcitabine and capecitabine have non-overlapping mechanism of activity. This phase I trial explored the combination of FDR gemcitabine plus capecitabine. METHODS Patients received gemcitabine (G) as… (More)

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