A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation

Abstract

Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progression, and therapy response in graft recipients are insufficient. Here… (More)
DOI: 10.1186/s13073-015-0246-z

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@inproceedings{Paul2015ADE, title={A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation}, author={Dirk S. Paul and Allison Jones and Rob S. Sellar and Neema P. Mayor and Andrew Feber and Amy P. Webster and Neuza Afonso and Ruhena Sergeant and Richard M. Szydlo and Jane F. Apperley and Martin Widschwendter and Stephen Mackinnon and Steven G. E. Marsh and Jos{\`e} Alejandro Madrigal and Vardhman K. Rakyan and Karl S. Peggs and Stephan Beck}, booktitle={Genome Medicine}, year={2015} }