A distinctive repertoire of cathepsins is expressed by juvenile invasive Fasciola hepatica.

@article{Cancela2008ADR,
  title={A distinctive repertoire of cathepsins is expressed by juvenile invasive Fasciola hepatica.},
  author={Martin Pablo Cancela and Daniel Acosta and Gabriel Rinaldi and Edileusa Silva and Rosario Duran and Leda Roche and Arnaldo Zaha and Carlos Garcia Carmona and Jose F Tort},
  journal={Biochimie},
  year={2008},
  volume={90 10},
  pages={1461-75}
}
Secreted cysteine proteases are relevant actors in parasite biology, taking part in critical host colonization roles such as traversing tissue barriers, immune evasion and nutrient digestion. In the trematode Fasciola hepatica, the initial step to successful infection of the mammalian host is the excystment of metacercariae and the invasion through the intestinal wall by the newly excysted juveniles (NEJ). While the cathepsin L-like cysteine proteinases secreted by the adult fluke have been… CONTINUE READING

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MEROPS: the peptidase database

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