A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression.

Abstract

We recently reported that germline mutations in BAP1 cause a familial tumor syndrome characterized by high penetrance for melanocytic tumors with distinct clinical and histologic features. Melanocytic neoplasms in affected individuals harbored BRAF mutations, showed loss of BAP1 expression, and histologically resembled so-called "atypical Spitz tumors… (More)
DOI: 10.1097/PAS.0b013e3182498be5

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@article{Wiesner2012ADS, title={A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression.}, author={Thomas Wiesner and Rajmohan Murali and Isabella Fried and L Cerroni and Klaus J. Busam and Heinz Kutzner and Boris C Bastian}, journal={The American journal of surgical pathology}, year={2012}, volume={36 6}, pages={818-30} }