A disequilibrium model for detecting genetic mutations for cancer.

Abstract

It has been recognized that genetic mutations in specific nucleotides may give rise to cancer via the alteration of signaling pathways. Thus, the detection of those cancer-causing mutations has received considerable interest in cancer genetic research. Here, we propose a statistical model for characterizing genes that lead to cancer through point mutations… (More)
DOI: 10.1016/j.jtbi.2010.04.019

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