A discussion of some statistical methods for separating within-pair associations from associations among all twins in research on fetal origins of disease.

@article{Dwyer2005ADO,
  title={A discussion of some statistical methods for separating within-pair associations from associations among all twins in research on fetal origins of disease.},
  author={Terence Dwyer and Leigh Blizzard},
  journal={Paediatric and perinatal epidemiology},
  year={2005},
  volume={19 Suppl 1},
  pages={
          48-53
        }
}
Twin data can be used to gain insights into the origin of associations between factors arising in fetal life and the risk of later disease. This is because twin data afford an opportunity to conduct paired analyses that take the influence of shared factors into account. When an association that is present in an unpaired analysis is present also in a paired analysis, there is evidence that the causal pathway linking the fetal factor and the disease may have a fetal origin. If the association… CONTINUE READING

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