A discrepancy resolved: human satellite cells are not preprogrammed to fast and slow lineages.

@article{Bonavaud2001ADR,
  title={A discrepancy resolved: human satellite cells are not preprogrammed to fast and slow lineages.},
  author={Sylvie Bonavaud and Onnik Agbulut and R{\'e}mi Nizard and Gilles D'honneur and Vincent Mouly and Gillian Butler-Browne},
  journal={Neuromuscular disorders : NMD},
  year={2001},
  volume={11 8},
  pages={747-52}
}
Satellite cells from chicken and mouse muscle when differentiated in vitro have been shown to display a myosin heavy chain phenotype that corresponds to the fibre from which they originated. Indirect evidence has suggested that this might not be the case for human satellite cells. In the present study we have compared the myosin heavy chain (MHC) profile expressed by differentiated cultures of satellite cells isolated from single fast or slow muscle fibres. The MHC composition of the isolated… CONTINUE READING

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