A direct androgenic involvement in the expression of human corticotropin-releasing hormone

Abstract

We investigated the possibility of a direct action of androgens on the expression of the human corticotropin-releasing hormone (CRH), which plays a central role in the hypothalamic–pituitary–adrenal (HPA)-axis. Colocalization of CRH and nuclear/cytoplasmic androgen receptor (AR) was found in neurons of the paraventricular nucleus (PVN) in the human… (More)
DOI: 10.1038/sj.mp.4001800

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