A differential effect of trypsin on pituitary gonadotropin-releasing hormone receptors from intact and ovariectomized rats. Evidence for the existence of two distinct receptor populations.

Abstract

The present report demonstrates that pituitary receptors for gonadotropin-releasing hormone generated following ovariectomy are susceptible to the action of trypsin while those present in intact metestrous females are not. The action of trypsin of gonadotropin-releasing hormone receptors in pituitary cells derived from ovariectomized rats was dependent on… (More)

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