A diagnostic protocol for evaluating nonimmediate reactions to aminopenicillins.

  title={A diagnostic protocol for evaluating nonimmediate reactions to aminopenicillins.},
  author={Antonio Romano and Donato Quaratino and Maina Di Fonso and Giuseppe Papa and Alberto Venuti and Giovanni Battista Gasbarrini},
  journal={The Journal of allergy and clinical immunology},
  volume={103 6},
BACKGROUND Maculopapular and urticarial rashes are nonimmediate manifestations common during aminopenicillin (AP) treatment, and the former often represent cell-mediated hypersensitivity. OBJECTIVES We sought to determine the significance and incidence of skin test reactions to APs in adults reporting adverse reactions during therapy with these beta-lactams and, particularly, to evaluate the potential of patch tests, delayed-reading skin tests, and challenges in the diagnosis of nonimmediate… CONTINUE READING


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